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KMID : 0356620020170050705
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Journal of Korean Society of Endocrinology
2002 Volume.17 No. 5 p.705 ~ p.712
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Lymphocytic Hypophysitis associated with Pregnancy
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Lee Seong-Jin
Lee Hyang-Lim
Jeong In-Kyung
Hong Eun-Gyoung
Choi Cheol-Soo
Kim Hyeon-Kyu
Kim Doo-Man
Yoo Jae-Myung
Ihm Sung-Hee
Choi Moon-Gi
Yoo Hyung-Joon
Park Sung-Woo
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Abstract
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Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland that is often recognized as a cause of hypopituitarism and may be due to the autoimmune pituitary destruction that usually occurs in women in the peripartum period. We report a rare case of lymphocytic hypophysitis in a 26 year-old woman presenting with nausea and headaches for 2 months after an artificial abortion of her second pregnancy. Magnetic resonance imaging, with enhancement, showed an expanding 1.0x1.0 cm sized sellar mass. The patient underwent transsphenoidal surgery with a preoperative diagnosis of pituitary macroadenoma. A histological examination revealed diffuse lymphocytes and plasma cells infiltration which are characteristic of lymphocytic hypophysitis. Here, we present the first reported case of a pregnant woman with lymphocytic hypophysitis with a review of the literature on this increasingly recognized condition.
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KEYWORD
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Lymphocytic Hypophysitis, Pregnancy
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